C22415

4-Chloranilin

98%

• Synonym(e): 1-Amino-4-chlorobenzene, 4-Chlorophenylamine, p-Chloroaniline
• Lineare Formel: ClC₆H₄NH₂
• CAS-Nummer: 106-47-8
• Molekulargewicht: 127.57
• Beilstein: 471359
• EG-Nummer: 203-401-0
• MDL-Nummer: MFCD00007835
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24892480
• NACRES: NA.22

Eigenschaften

• Dampfdichte: 4.4 (vs air)
• Qualitätsniveau: 200
• Dampfdruck: 0.15 mmHg ( 25 °C)
• Assay: 98%
• Form: chips; crystals or chunks
• bp: 232 °C (lit.)
• mp (Schmelzpunkt): 67-70 °C (lit.)
• SMILES String: Nc1ccc(Cl)cc1
• InChI: 1S/C6H6ClN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2
• InChIKey: QSNSCYSYFYORTR-UHFFFAOYSA-N

Beschreibung

Anwendung

4-Chloroaniline can undergo:

• Allylation in the presence of ultrasonication to form N-allyl-4-chloroaniline, a precursor for bioactive compounds containing indole and dihydroindole nucleus.
• Povarov reaction with cyclopentadiene to form C-2 aliphatic substituted tetrahydroquinolines.
• Mannich reaction with aldehydes and cyclic ketones to form β-amino carbonyl compounds.
• Nitration to form 4-chloro-3-nitroaniline in the presence of guanidinium nitrate.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H301 + H311 + H331,H317,H350,H410
• P-Sätze: P202 - P273 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Skin Sens. 1
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 248.0 °F - closed cup
• Flammpunkt (°C): 120.0 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges