B80100

2-Brompyridin

99%

• Synonym(e): β-Bromopyridine, 2-Pyridyl bromide, Pyridin-2-yl bromide, o-Bromopyridine
• Empirische Formel (Hill-System): C₅H₄BrN
• CAS-Nummer: 109-04-6
• Molekulargewicht: 158.00
• Beilstein: 105789
• EG-Nummer: 203-641-6
• MDL-Nummer: MFCD00006219
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24892038
• NACRES: NA.22

Eigenschaften

• Assay: 99%
• Form: liquid
• Brechungsindex: n20/D 1.572 (lit.)
• bp: 192-194 °C (lit.)
• Dichte: 1.657 g/mL at 25 °C (lit.)
• SMILES String: Brc1ccccn1
• InChI: 1S/C5H4BrN/c6-5-3-1-2-4-7-5/h1-4H
• InChIKey: IMRWILPUOVGIMU-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-Bromopyridine is an organic compound that is widely used as a building block in organic synthesis. It is also used as intermediate for the synthesis of Pyridine derivatives.

Anwendung

2-Bromopyridine can be used as:

• A building block in the formation of C−N bond by various cross coupling reactions.
• A reactant in Negishi cross-coupling reaction with aryl halides catalyzed by palladium.
• A reactant in the synthesis of 2′-pyridyldifluoroacetate with ethyl bromodifluoroacetate in presence of copper as a catalyst.

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301,H310,H315,H319,H335
• P-Sätze: P261 - P262 - P280 - P301 + P310 - P302 + P352 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 2 Dermal - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 195.1 °F - closed cup
• Flammpunkt (°C): 90.6 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter