924520

4-Methoxybenzylchlorid

• Synonym(e): 4-Chlormethyl-anisol
• Lineare Formel: CH₃OC₆H₄CH₂Cl
• CAS-Nummer: 824-94-2
• Molekulargewicht: 156.61
• Beilstein: 606667
• MDL-Nummer: MFCD00000915
• UNSPSC-Code: 41116105
• NACRES: NA.22

Eigenschaften

• Form: liquid
• Qualitätsniveau: 100
• Brechungsindex: n20/D 1.548 (lit.)
• bp: 117-118 °C/14 mmHg (lit.)
• mp (Schmelzpunkt): −1 °C (lit.)
• Dichte: 1.155 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro
• Lagertemp.: 2-8°C
• SMILES String: COc1ccc(CCl)cc1
• InChI: 1S/C8H9ClO/c1-10-8-4-2-7(6-9)3-5-8/h2-5H,6H2,1H3
• InChIKey: MOHYOXXOKFQHDC-UHFFFAOYSA-N

Beschreibung

Anwendung

4-Methoxybenzyl chloride can be used as a reactant:

• To synthesize 4-methoxybenzyl esters by reacting with cyclic anhydrides.
• In the mono-alkylation of trans-1,2-diaminocyclohexane.

It can also be used as a:

• Protecting group for amino acids during peptide synthesis using triethylamine as a base.
• Co-catalyst in the intramolecular carboamination of aminodienes to N-heterocyclesvia benzyl-group transfer.

Sicherheitshinweise

• Piktogramme: GHS05
• Signalwort: Danger
• H-Sätze: H314
• P-Sätze: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Gefahreneinstufungen: Eye Dam. 1 - Skin Corr. 1B
• Lagerklassenschlüssel: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): 228.2 °F - closed cup
• Flammpunkt (°C): 109 °C - closed cup