910813

mPEG₂₄-NHS

• Synonym(e): Methoxypolyethylene glycol acetic acid N-succinimidyl ester, mPEG NHS
• Empirische Formel (Hill-System): C₅₆H₁₀₇NO₂₉
• CAS-Nummer: 174569-25-6
• Molekulargewicht: 1258.44
• MDL-Nummer: MFCD28385538
• UNSPSC-Code: 43211915
• NACRES: NA.23

Eigenschaften

• Assay: 95% (HPLC)
• Form: solid
• Mol-Gew.: average M_n 1,250 (by NMR)
• Eignung der Reaktion: reagent type: chemical modification reagent; reactivity: amine reactive
• Farbe: white to off-white
• Ω-Ende: NHS ester
• α-Ende: methoxy
• Polymerarchitektur: shape: linear; functionality: monofunctional
• Lagertemp.: −20°C

Beschreibung

Anwendung

Polyethylene glycols (PEGs) are FDA approved hydrophilic polymers. They are non-toxic, non-immunogenic and non-antigenic, and are widely used in a variety of biomedical applications such as bioconjugation, drug delivery, surface functionalization, and tissue engineering. PEG-NHS is an amine reactive PEG that can react to amino groups of lysine(s) on proteins or other biologics; reaction occurs at room temperature in <1hr at pH 7-8. Stable linker between PEG and NHS ester.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): >230.0 °F
• Flammpunkt (°C): > 110 °C