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900649

Sigma-Aldrich

Methoxy poly(ethylene glycol)-block-poly(ε-caprolactone)

2k-2k

Synonym(e):

mPEG-b-PCL, mPEG-PCL

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About This Item

Lineare Formel:
CH3O(CH2CH2O)n(COCH2CH2CH2CH2CH2O)mH
UNSPSC-Code:
12161904
NACRES:
NA.23

Qualitätsniveau

100

Form

powder

Mol-Gew.

PCL average Mn ~2,000
PEG average Mn ~2,000

Übergangstemp.

flash point >230 °F
Tm 47-51 °C

Lagertemp.

2-8°C

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Anwendung

Biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These materials have been used as a block copolymer surfactant as well as in control release and nanoparticle formulation for drug delivery applications. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

>230.0 °F

Flammpunkt (°C)

> 110 °C

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
MKCQ6164
MKCD0539

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Simple solvothermalsynthesis of hydrophobic magnetic monodispersed Fe3O4 nanoparticles.
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Mat. Res. Bul., 48(2), 416-421 (2013)
On the mechanism of formation of vesicles from poly(ethylene oxide)-block-poly(caprolactone) copolymers.
Adams DJ, et al.
Soft Matter, 5, 3086-3096 (2009)
Xu Wen Ng et al.
Journal of pharmaceutical sciences, 103(11), 3631-3640 (2014-09-17)
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Xu Wen Ng et al.
Drug delivery and translational research, 5(5), 469-479 (2015-06-24)
Timolol maleate (TM) has been used for many years for the reduction of intraocular pressure (IOP) in glaucoma patients. However, the topical mode of administration (eyedrops) is far from optimal because of the issues of low bioavailability, high drug wastage
Bhuvana S Doddapaneni et al.
Journal of controlled release : official journal of the Controlled Release Society, 220(Pt A), 503-514 (2015-11-19)
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Artikel

Polymersomes for Drug Delivery

The development of drugs that target specific locations within the human body remains one of the greatest challenges in biomedicine today.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

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