900600

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid

≥95%

• Synonym(e): Carboxyl sulfonyl fluoride alkyne, Probe building block
• Empirische Formel (Hill-System): C₁₂H₁₃FO₄SSi
• CAS-Nummer: 2088829-06-3
• Molekulargewicht: 300.38
• MDL-Nummer: MFCD30737995
• UNSPSC-Code: 12352106
• NACRES: NA.22

Eigenschaften

• Assay: ≥95%
• Form: solid
• Eignung der Reaktion: reagent type: cross-linking reagent
• Verfügbarkeit: available only in USA
• Lagertemp.: −20°C
• SMILES String: O=S(C1=CC(C#C[Si](C)(C)C)=CC(C(O)=O)=C1)(F)=O

Beschreibung

Anwendung

3-(Fluorosulfonyl)-5-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Sonstige Hinweise

Technology Spotlight: Trifuctional Probe Building Blocks

Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H242,H315,H319
• P-Sätze: P210 - P235 - P302 + P352 - P305 + P351 + P338 - P370 + P378 - P403
• Gefahreneinstufungen: Eye Irrit. 2 - Self-react. C - Skin Irrit. 2
• Lagerklassenschlüssel: 5.2 - Organic peroxides and self-reacting hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable