776173

5-Norbornene-2-acetic acid succinimidyl ester

97%

• Synonym(e): 2,5-Dioxopyrrolidin-1-yl 2-(bicyclo[2.2.1]hept-5-en-2-yl)acetate, 5-Norbornene-2-acetic acid NHS, Bicyclo[2.2.1]hept-5-ene-2-acetic acid N-hydroxysuccinimide ester, Bicyclo[2.2.1]hept-5-ene-2-acetic acid, 2,5-dioxo-1-pyrrolidinyl ester
• Empirische Formel (Hill-System): C₁₃H₁₅NO₄
• CAS-Nummer: 1234203-45-2
• Molekulargewicht: 249.26
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 329767816
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Form: solid
• Eignung der Reaktion: reaction type: click chemistry; reagent type: linker
• mp (Schmelzpunkt): 115-120 °C
• Funktionelle Gruppe: NHS ester
• Lagertemp.: 2-8°C
• SMILES String: O=C(N1OC(C[C@H]2[C@@H]3C=C[C@@H](C3)C2)=O)CCC1=O
• InChI: 1S/C13H15NO4/c15-11-3-4-12(16)14(11)18-13(17)7-10-6-8-1-2-9(10)5-8/h1-2,8-10H,3-7H2
• InChIKey: AOGNOQQTUYLDKN-UHFFFAOYSA-N

Beschreibung

Anwendung

Succinimidyl ester functionalized norbornene. Succinimidyl ester group will react with amine containing compounds such as lysine residues on proteins/peptides. Norbornene has been shown to react with 1; 2; 4; 5-tetrazines in an inverse electron demand Diels-Alder cycloaddition reaction which is a bioorthogonal reaction demonstrated to be useful in biological imaging applications.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable