752940

(Trimethylphosphoranylidene)acetonitrile solution

0.5 M in THF

• Synonym(e): CMMP, Cyanomethylenetrimethylphosphorane solution
• Empirische Formel (Hill-System): C₅H₁₀NP
• CAS-Nummer: 176325-83-0
• Molekulargewicht: 115.11
• MDL-Nummer: MFCD17013403
• UNSPSC-Code: 12352000
• PubChem Substanz-ID: 329766326
• NACRES: NA.22

Eigenschaften

• Form: liquid
• Qualitätsniveau: 100
• Konzentration: 0.5 M in THF
• Dichte: 0.896 g/mL at 25 °C
• Funktionelle Gruppe: nitrile; phosphine
• Lagertemp.: 2-8°C
• SMILES String: CP(C)(C)=CC#N
• InChI: 1S/C5H10NP/c1-7(2,3)5-4-6/h5H,1-3H3
• InChIKey: KJFJIEHJCVSAKJ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

(Trimethylphosphoranylidene)acetonitrile is a reagent generally employed in the Wittig olefination of less reactive carboxylic acid compounds like esters, N-Boc lactams, lactones, and imides to give α,β-unsaturated nitriles. It is also used as an alternate reagent for Mitsonobu reaction by replacing DEAD/PPh₃ for the alkylation of C-H and N-H bonds.

Sonstige Hinweise

If precipitate is observed, warm gently to resolubilize

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H225,H302,H319,H335,H336,H351
• P-Sätze: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Zusätzliche Gefahrenhinweise: EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): -5.8 °F - closed cup
• Flammpunkt (°C): -21.0 °C - closed cup