746118

Sodium difluoroheptylazidosulfinate

95%

• Synonym(e): Baran DAAS-Na Reagent, Sodium 1,1-difluoro-7-azido-heptylsulfinate, Sodium 7-azido-1,1-difluoroheptanesulfinate
• Empirische Formel (Hill-System): C₇H₁₂F₂N₃NaO₂S
• CAS-Nummer: 1450912-63-6
• Molekulargewicht: 263.24
• UNSPSC-Code: 12352125
• PubChem Substanz-ID: 329765744
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: solid
• Eignung der Reaktion: reaction type: C-C Bond Formation; reagent type: catalyst; reaction type: C-H Activation; reagent type: linker
• Funktionelle Gruppe: azide; fluoro; sulfinic acid
• Lagertemp.: 2-8°C
• SMILES String: [Na+].[O-]S(=O)C(F)(F)CCCCCCN=[N+]=[N-]
• InChI: 1S/C7H13F2N3O2S.Na/c8-7(9,15(13)14)5-3-1-2-4-6-11-12-10;/h1-6H2,(H,13,14);/q;+1/p-1
• InChIKey: FFNHIEJQAMGBCZ-UHFFFAOYSA-M

Beschreibung

Anwendung

Within heteroarene platforms, DAAS-Na allows for the direct introduction of a difluoroalkyl chain carrying an azide group, which is designed for the purpose of bioconjugation. Through a Huisgen cycloaddition (a "click" reaction), the azide moiety can then be reacted with a terminal alkyne that is bound to a functional molecule such as biomacromolecules. This effectively allows for a covalent linkage between a heteroarene and any target molecule, for example, between a heteroarene-containing drug and an antibody. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles.

Learn More at the Professor and Product Portal of Professor Phil S. Baran.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable