714151

Fmoc-β-azido-Ala-OH

≥98.0% (HPLC), for peptide synthesis

• Synonym(e): (S)-3-Azido-2-(Fmoc-amino)-propionsäure, Fmoc-3-azido-L-alanin
• Empirische Formel (Hill-System): C₁₈H₁₆N₄O₄
• CAS-Nummer: 684270-46-0
• Molekulargewicht: 352.34
• MDL-Nummer: MFCD11052919
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 329763258
• NACRES: NA.26

Eigenschaften

• Produktbezeichnung: Fmoc-β-azido-Ala-OH, ≥98.0% (HPLC)
• Qualitätsniveau: 100
• Assay: ≥98.0% (HPLC)
• Form: lumps
• Optische Aktivität: [α]/D -10.0±1.0°, c = 1 in DMF
• Eignung der Reaktion: reaction type: Fmoc solid-phase peptide synthesis; reaction type: click chemistry
• Verunreinigungen: 15.3-16.5% nitrogen; 60.1-62.5% carbon
• Anwendung(en): peptide synthesis
• Funktionelle Gruppe: Fmoc
• Lagertemp.: 2-8°C
• SMILES String: OC(=O)[C@H](CN=[N+]=[N-])NC(=O)OCC1c2ccccc2-c3ccccc13
• InChI: 1S/C18H16N4O4/c19-22-20-9-16(17(23)24)21-18(25)26-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H,21,25)(H,23,24)/t16-/m0/s1
• InChIKey: ZITYCUDVCWLHPG-INIZCTEOSA-N

Beschreibung

Anwendung

Fmoc-β-azido-Ala-OH chloride is a general N-terminal protected reagent used in the solid phase peptide synthesis. Azido group allows it to undergo copper-mediated click chemistry reactions.
It can be used in:

• Synthesis of α-N-acetylgalactosamine (α-GalNAc) linked antifreeze glycopeptides (AFGPs).
• Synthesis of stimuli-responsive multifunctional peptide gatekeepers for drug delivery applications.
• Synthesis of triazole-linked glycopeptides via Cu(I)-catalyzed 1,3-dipolar cycloaddition (CuAAC).

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves