687901

4-(Trifluormethoxy)phenylmagnesiumbromid

0.5 M in THF

• Empirische Formel (Hill-System): C₇H₄BrF₃MgO
• Molekulargewicht: 265.31
• MDL-Nummer: MFCD09842767
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 329760826
• NACRES: NA.22

Eigenschaften

• Form: liquid
• Eignung der Reaktion: reaction type: Grignard Reaction
• Konzentration: 0.5 M in THF
• Dichte: 0.975 g/mL at 25 °C
• SMILES String: FC(F)(F)Oc1ccc([Mg]Br)cc1
• InChI: 1S/C7H4F3O.BrH.Mg/c8-7(9,10)11-6-4-2-1-3-5-6;;/h2-5H;1H;/q;;+1/p-1
• InChIKey: UFMHNMPAQCQXMW-UHFFFAOYSA-M

Beschreibung

Anwendung

Reactant for:

• Preparation of chromanol derivatives as novel class of CETP inhibitors for treatment of cardiovascular disease
• Pd-catalyzed cross coupling
• Preparation of indazole-pyridine derivatives as protein kinase B/Akt inhibitors with reduced hypotension, via Stille coupling, Mitsunobu reaction and copper-catalyzed aziridine ring-opening reaction

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H225,H302,H314,H335,H336,H351
• P-Sätze: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
• Zielorgane: Respiratory system
• Zusätzliche Gefahrenhinweise: EUH014,EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): -22.0 - -4.0 °F - closed cup
• Flammpunkt (°C): -30 - -20 °C - closed cup