637386

2-Chlor-5-pyridinboronsäure

≥95.0%

• Synonym(e): 6-Chlor-3-Pyridinylboronsäure
• Empirische Formel (Hill-System): C₅H₅BClNO₂
• CAS-Nummer: 444120-91-6
• Molekulargewicht: 157.36
• MDL-Nummer: MFCD03094998
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24882850
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95.0%
• Form: solid
• mp (Schmelzpunkt): 165 °C (lit.)
• Funktionelle Gruppe: chloro
• SMILES String: OB(O)c1ccc(Cl)nc1
• InChI: 1S/C5H5BClNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3,9-10H
• InChIKey: WPAPNCXMYWRTTL-UHFFFAOYSA-N

Beschreibung

Anwendung

6-Chloro-3-pyridinylboronic acid can be used:

• To prepare biologically significant 3-arylcoumarins by reacting with 3-chlorocoumarin through Suzuki reaction.
• As a substrate in the synthesis of 11-(pyridinylphenyl)steroid with progesterone agonist/antagonist profile.
• As a substrate in the preparation of α- secondary and tertiary pyridines by the reaction of pyridotriazoles with boronic acids.
• As a substrate in the palladium-catalyzed α-arylation of saturated cyclic amines and N-methyl amines.

Sonstige Hinweise

Contains varying amounts of anhydride

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves