540099

(R)-Phenylethylenoxid

97%, optical purity ee: 97% (GLC)

• Synonym(e): (R)-(+)-Styroloxid, (R)-Phenyloxiran
• Empirische Formel (Hill-System): C₈H₈O
• CAS-Nummer: 20780-53-4
• Molekulargewicht: 120.15
• Beilstein: 1984
• MDL-Nummer: MFCD00066210
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24878440
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• Optische Aktivität: [α]20/D +33°, neat
• Optische Reinheit: ee: 97% (GLC)
• Expl.-Gr.: ~22 %
• Brechungsindex: n20/D 1.534 (lit.)
• bp: 89-90 °C/23 mmHg (lit.)
• Dichte: 1.051 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: ether; phenyl
• SMILES String: C1O[C@@H]1c2ccccc2
• InChI: 1S/C8H8O/c1-2-4-7(5-3-1)8-6-9-8/h1-5,8H,6H2/t8-/m0/s1
• InChIKey: AWMVMTVKBNGEAK-QMMMGPOBSA-N

Beschreibung

Anwendung

Used to produce a homologated epoxide as part of a synthetic approach to (+)-allosedamine.

(R)-(+)-Styrene oxide can be used:

• As a chiral initiator in the synthesis of 5-pyrimidyl alkanol from its corresponding aldehyde using diisopropylzinc.
• As a substrate in the stereoselective intermolecular O-alkylation of phenols with epoxides via Friedel–Crafts-type reaction.
• As a substrate in the ring-opening reactions of epoxides with alcohols, carboxylic acids, and thiols using the AlPW₁₂O₄₀ catalyst.

Rechtliche Hinweise

Manufactured under license by Shasun Chemicals and Drugs Limited, using Jacobsen HKR technology.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H312,H319,H350
• P-Sätze: P202 - P264 - P280 - P302 + P352 + P312 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Carc. 1B - Eye Irrit. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): 176.0 °F - closed cup
• Flammpunkt (°C): 80 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter