530301

2-Chlormethyl-3,4-dimethoxypyridiniumchlorid -hydrochlorid

97%

• Synonym(e): 2-(Chloromethyl)-3,4-dimethoxypyridinium hydrochloride
• Empirische Formel (Hill-System): C₈H₁₁Cl₂NO₂
• CAS-Nummer: 72830-09-2
• Molekulargewicht: 224.08
• Beilstein: 5360726
• EG-Nummer: 416-440-5
• MDL-Nummer: MFCD02181083
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24877740
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• mp (Schmelzpunkt): 155 °C (dec.) (lit.)
• Funktionelle Gruppe: chloro
• SMILES String: Cl[H].COc1ccnc(CCl)c1OC
• InChI: 1S/C8H10ClNO2.ClH/c1-11-7-3-4-10-6(5-9)8(7)12-2;/h3-4H,5H2,1-2H3;1H
• InChIKey: YYRIKJFWBIEEDH-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride (CDP) can be synthesized using maltol as a starting material. CDP and DMS (dimethyl sulfate) are used in the preparation of pantoprazole sodium (PPS), an antiulcerative drug. The quantification of CDP and DMS in PPS can be done simultaneously by gas chromatography–mass spectrometry (GC-MS) method.

Anwendung

2-(Chloromethyl)-3,4-dimethoxypyridine hydrochloride may be used as a precursor for the preparation [(2-pyridyl)-2-ethyl]-[3,4-dimethoxy-(2-pyridylmethyl)]-N-methylamine.

Sicherheitshinweise

• Piktogramme: GHS08,GHS05,GHS07,GHS09
• Signalwort: Danger
• H-Sätze: H302 + H312,H315,H317,H318,H373,H411
• P-Sätze: P273 - P280 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves