512834

3-(Hydroxymethyl)phenylborsäure

≥95%

• Synonym(e): 3-Hydroxymethylbenzolboronsäure
• Lineare Formel: HOCH₂C₆H₄B(OH)₂
• CAS-Nummer: 87199-15-3
• Molekulargewicht: 151.96
• MDL-Nummer: MFCD01317846
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24873658
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95%
• mp (Schmelzpunkt): 95-99 °C (lit.)
• Funktionelle Gruppe: hydroxyl
• SMILES String: OCc1cccc(c1)B(O)O
• InChI: 1S/C7H9BO3/c9-5-6-2-1-3-7(4-6)8(10)11/h1-4,9-11H,5H2
• InChIKey: HGTDLKXUWVKLQX-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant involved in:

• Copper-mediated trifluoromethylation
• Copper-catalyzed transformations from arylboronic acids in water
• Mitsunobu, Suzuki, and amidation reactions with hydroxyphenylamino bromopyrazinecarboxylate

Reactant involved in the synthesis of biologically active molecules including:

• Mycobacterium tuberculosis H37Rv chorismate mutase inhibitors via Suzuki coupling reactions
• HIV protease inhibitors with antiviral activity against drug-resistant viruses
• Pyrrole derivatives for use as PDE4B inhibitors

Sonstige Hinweise

Contains varying amounts of anhydride

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)