465313

1-Methylindol-3-carbonsäure

97%

• Empirische Formel (Hill-System): C₁₀H₉NO₂
• CAS-Nummer: 32387-21-6
• Molekulargewicht: 175.18
• MDL-Nummer: MFCD01321244
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24870267

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• mp (Schmelzpunkt): 197-200 °C (dec.) (lit.)
• Funktionelle Gruppe: carboxylic acid
• SMILES String: Cn1cc(C(O)=O)c2ccccc12
• InChI: 1S/C10H9NO2/c1-11-6-8(10(12)13)7-4-2-3-5-9(7)11/h2-6H,1H3,(H,12,13)
• InChIKey: HVRCLXXJIQTXHC-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1-Methylindole-3-carboxylic acid is an indole derivative that can be prepared by the oxidation of 1-methylindole-3-aldehyde with alkaline potassium permanganate.

Anwendung

• Reactant for preparation of bisindolyl pyrimidinones analogs of PKC inhibitor LY333531
• Reactant for preparation of (heteroaryl)(carboxamido)arylpyrrole derivatives as Cdc7 kinase inhibitors, antitumor and antiproliferative agents
• Reactant for preparation of (pyrrolidinylmethoxy)cyclohexanecarboxylic acids as antigen-4 (VLA-4) antagonists
• Reactant for preparation of EphB3 receptor tyrosine kinase inhibitors
• Reactant for preparation of pyrazolodiazepine derivatives as human P2X7 receptor antagonists
• Reactant for preparation of potent nonpeptidic urotensin II receptor agonists
• Reactant for preparation of pyrrolizidine esters, amides, and ureas as 5-HT4 receptor ligands

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves