368830

1,3-Dichlorisochinolin

97%

• Empirische Formel (Hill-System): C₉H₅Cl₂N
• CAS-Nummer: 7742-73-6
• Molekulargewicht: 198.05
• MDL-Nummer: MFCD00034750
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24862933
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 97%
• mp (Schmelzpunkt): 121-122 °C (lit.)
• SMILES String: Clc1cc2ccccc2c(Cl)n1
• InChI: 1S/C9H5Cl2N/c10-8-5-6-3-1-2-4-7(6)9(11)12-8/h1-5H
• InChIKey: BRGZEQXWZWBPJH-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1,3-Dichloroisoquinoline undergoes Pd(PPh₃)₄ catalyzed regioselective coupling with arylboronic acids to afford to 1-aryl-3-chloroisoquinolines. Reaction of amine with 1,3-dichloroisoquinoline has been studied. Regioselectivity of the Stille coupling reaction of (1-ethoxyvinyl)tri(n-butyl)stannane with 1,3-dichloroisoquinoline has been investigated.

Anwendung

1,3-Dichloroisoquinoline may be used in the facile synthesis of 1,3,4-trisubstituted isoquinoline derivatives.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves