140775

Tetrabutylammoniumiodid

reagent grade, 98%

• Synonym(e): TBAI
• Lineare Formel: (CH₃CH₂CH₂CH₂)₄N(I)
• CAS-Nummer: 311-28-4
• Molekulargewicht: 369.37
• Beilstein: 3916152
• EG-Nummer: 206-220-5
• MDL-Nummer: MFCD00011636
• UNSPSC-Code: 12352107
• PubChem Substanz-ID: 24848477
• NACRES: NA.22

Eigenschaften

• Qualität: reagent grade
• Qualitätsniveau: 200
• Assay: 98%
• Form: solid
• mp (Schmelzpunkt): 141-143 °C (lit.)
• SMILES String: [I-].CCCC[N+](CCCC)(CCCC)CCCC
• InChI: 1S/C16H36N.HI/c1-5-9-13-17(14-10-6-2,15-11-7-3)16-12-8-4;/h5-16H2,1-4H3;1H/q+1;/p-1
• InChIKey: DPKBAXPHAYBPRL-UHFFFAOYSA-M

Beschreibung

Anwendung

Tetrabutylammonium iodide (TBAI) has been used as a catalyst in the following reactions:

• Synthesis of O-benzyl-N-Boc-L-tyrosine benzyl ester from N-Boc-L-tyrosine.
• Conversion of 8-fluoro-1-aminonaphthalene into 1-(8-fluoro-naphthalen-1-yl)piperazine hydrochloride.
• Synthesis of 1-(2,4-dichlorophenyl)-5-(4-(4-iodobut-1-ynyl)phenyl)-4-methyl-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide from 4-(4-(1-(2,4-dichlorophenyl)-4-methyl-3-(piperidin-1-ylcarbamoyl)-1H-pyrazol-5-yl)phenyl)but-3-yn-1-yl methanesulfonate.

Other reactions where TBAI can be used as a catalyst:

• TBAI-tert-butyl hydroperoxide system can catalyze the conversion of α-methyl styrene derivatives into allylic sulfones by reacting with sulfonylhydrazides under metal-free conditions.
• Palladium(0)-catalyzed cross-coupling between benzylic zinc bromides and aryl or alkenyl triflates.
• Three-component coupling of amines, carbon dioxide, and halides to form carbamates in the presence of cesium carbonate.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 - H315 - H319
• P-Sätze: P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves