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14050

Sigma-Aldrich

Berberinchlorid Hydrat

technical, ≥90% (AT)

Synonym(e):

Naturgelb 18

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About This Item

Empirische Formel (Hill-System):
C20H18ClNO4 · xH2O
CAS-Nummer:
141433-60-5
Molekulargewicht:
371.81 (anhydrous basis)
Farbindexnummer:
75160
EG-Nummer:
211-195-9
MDL-Nummer:
MFCD00011939
UNSPSC-Code:
12352103
PubChem Substanz-ID:
57647132
NACRES:
NA.22

Qualität

technical

Assay

≥90% (AT)

Form

powder

mp (Schmelzpunkt)

204-206 °C (dec.)

SMILES String

[Cl-].COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC

InChI

1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1

InChIKey

VKJGBAJNNALVAV-UHFFFAOYSA-M

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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Lamyae El Khalki et al.
Molecules (Basel, Switzerland), 25(3) (2020-01-30)
Triple negative breast cancer (TNBC) is an aggressive breast cancer subtype. Non-available targeted therapy for TNBC represents its biggest treatment challenge. Thus, finding new promising effective drugs is urgently needed. In the present study, we investigated how berberine, a natural
Fatma Gizem Avci et al.
Fitoterapia, 139, 104371-104371 (2019-10-20)
Extrusion of drugs or drug-like compounds through bacterial efflux pumps is a serious health issue that leads to loss in drug efficacy. Combinatorial therapies of low-efficacy drugs with efflux pump inhibitors may help to restore the activities of such drugs.
Cemile Selin Aksoy et al.
Microbial pathogenesis, 149, 104542-104542 (2020-10-04)
A plethora of natural products emerges as attractive molecules in the struggle against antibiotic resistance. These molecules impose their bioactivities not only alone but also in combinations as well, which further enhances their effects. Berberine is a well-known isoquinoline alkaloid
Victor P Bagla et al.
BMC complementary and alternative medicine, 14, 383-383 (2014-10-09)
Different parts of Podocarpus henkelii have been used in many cultures around the world to treat ailments such as cholera, stomach diseases, rheumatism, cancer, canine distemper in dogs and gall sickness in cattle. The aim of this study was to
Li Jia et al.
Mediators of inflammation, 2020, 9419085-9419085 (2020-10-17)
Berberine (BER), a natural isoquinoline alkaloid, has been demonstrated to have appreciable anticolitis effects. Nevertheless, the protective mechanism of BER in ulcerative colitis (UC) is barely understood. The present study was aimed at exploring the therapeutic efficacy of BER on
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