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Merck

CACNA1F

calcium channel, voltage-dependent, L type, alpha 1F subunit

Synonyme:
AIED, COD3, COD4, CORDX, CORDX3, CSNB2, CSNB2A, CSNBX2, Cav1.4, Cav1.4alpha1, JM8, JMC8, OA2
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(778) Summary: This gene encodes a member of the alpha-1 subunit family; a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been shown to cause incomplete X-linked congential stationary night blindness type 2 (CSNB2). [provided by RefSeq, Feb 2012]
  • Mouse(54652) calcium channel, voltage-dependent, alpha 1F subunit
  • Rat(114493) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • sheep(101104552) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • domestic guinea pig(100720484) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • naked mole-rat(101722090) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • Zebrafish(386662) calcium channel, voltage-dependent, alpha 1F subunit
  • dog(480915) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • cow(509779) calcium channel, voltage-dependent, L type, alpha 1F subunit
  • domestic cat(101080870) calcium channel, voltage-dependent, L type, alpha 1F subunit

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Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
Gabapentin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Gabapentin -Lösung, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Gabapentin -Lösung, 10 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Pregabalin, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CACNA1F antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Verapamil -hydrochlorid, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Amlodipinbesilat, ≥98% (HPLC),
Spezies
human
Amlodipinbesilat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Nicardipin -hydrochlorid, powder, ≥98%,
Spezies
human
Verapamil hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CACNA1F,
Spezies
human