913669

Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid

• Sinónimos: N-(2-((2-Aminoethyl)disulfaneyl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 2,2,2-trifluoroacetate, Biotin-SS-NH₂ TFA, Biotin-cystamine TFA, Cleavable biotin linker
• Fórmula empírica (notación de Hill): C₁₆H₂₇F₃N₄O₄S₃
• Número de CAS: 880491-09-8
• Peso molecular: 492.60
• MDL number: MFCD34166204
• UNSPSC Code: 12352106
• NACRES: NA.22

Propiedades

• form: powder
• Quality Level: 100
• storage temp.: −20°C
• SMILES string: OC(C(F)(F)F)=O.NCCSSCCNC(CCCC[C@H]1[C@]2([H])[C@](NC(N2)=O)([H])CS1)=O
• InChI: 1S/C14H26N4O2S3.C2HF3O2/c15-5-7-22-23-8-6-16-12(19)4-2-1-3-11-13-10(9-21-11)17-14(20)18-13;3-2(4,5)1(6)7/h10-11,13H,1-9,15H2,(H,16,19)(H2,17,18,20);(H,6,7)/t10-,11-,13-;/m0./s1
• InChI key: IEBCHCOZFAGWJW-SQRKDXEHSA-N

Descripción

Application

Biotinamidoethyldisulfanyl(2-aminoethane) trifluoroacetic acid (Biotin-SS-NH₂ TFA) is a cleavable, biotinylated crosslinkers. The linker can also be used for synthesis of chemical biology tools for labeling target proteins in biological experiments and assays. It possesses dual functionality: enrichment via the biotin and an embedded disulfide bridge for cleavage under reducing conditions.

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Other Notes

Fluorometric assay for tissue transglutaminase-mediated transamidation activity

Convenient Synthesis of Photoaffinity Probes and Evaluation of Their Labeling Abilities

A simple photo-affinity labeling protocol

Información de seguridad

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable