M5308

L-Methionine

99.0-101.0%, suitable for cell culture, BioXtra, non-animal source

• Synonym(s): (S)-2-Amino-4-(methylmercapto)butyric acid, L-2-Amino-4-(methylthio)butanoic acid
• Linear Formula: CH₃SCH₂CH₂CH(NH₂)CO₂H
• CAS Number: 63-68-3
• Molecular Weight: 149.21
• Beilstein: 1722294
• EC Number: 200-562-9
• MDL number: MFCD00063097
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24896818
• NACRES: NA.26

Properties

• product name: L-Methionine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%
• biological source: non-animal source
• Quality Level: 300
• Agency: USP/NF; meets EP testing specifications; meets JP testing specifications; meets USP testing specifications
• product line: BioXtra
• Assay: 99.0-101.0%
• form: powder
• quality: meets EP, JP, USP testing specifications
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, tested
• color: white
• mp: 284 °C (dec.) (lit.)
• solubility: H₂O: 25 mg/mL
• application(s): peptide synthesis; pharmaceutical (small molecule)
• SMILES string: CSCC[C@H](N)C(O)=O
• InChI: 1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
• InChI key: FFEARJCKVFRZRR-BYPYZUCNSA-N
• Gene Information: rat ... Ggt1(116568)

Description

Application

L-Methionine has been used as a component of media to culture various cancer cells and to study its effects on the cell cycle. It has also been used as a component of DMEM medium to culture satellite cells from the white muscle of trouts.

Biochem/physiol Actions

Methionine is an essential amino acid which acts a precursor for transmethylation and transsulphuration. In proteins, L-methionine is the biologically active form. The adenosylation of methionine results in the formation of S-adenosyl-L-methionine (SAM), which serves as a methyl donor to various substances. L-Methionine′s metabolic product glutathione is known to regulate immune response and has antiviral action.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves