A16602
DL-N-Acetylhomocysteine thiolactone
98%
Synonym(s):
2-Acetamido-4-mercaptobutyric acid γ-thiolactone
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All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C6H9NO2S
CAS Number:
Molecular Weight:
159.21
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
98%
form
powder
mp
109-111 °C (lit.)
SMILES string
CC(=O)NC1CCSC1=O
InChI
1S/C6H9NO2S/c1-4(8)7-5-2-3-10-6(5)9/h5H,2-3H2,1H3,(H,7,8)
InChI key
NRFJZTXWLKPZAV-UHFFFAOYSA-N
Application
<ul>
<li><strong>Ultrasonic synthesis of stable oil filled microcapsules:</strong> This study explores the ultrasonic synthesis of oil-filled microcapsules using thiolated chitosan, potentially involving derivatives like N-Acetylhomocysteine thiolactone for improved stability and functional properties. The research provides insights into advanced microencapsulation techniques relevant in pharmaceutical and industrial applications (
<li><strong>Ultrasonic synthesis of stable oil filled microcapsules:</strong> This study explores the ultrasonic synthesis of oil-filled microcapsules using thiolated chitosan, potentially involving derivatives like N-Acetylhomocysteine thiolactone for improved stability and functional properties. The research provides insights into advanced microencapsulation techniques relevant in pharmaceutical and industrial applications (
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Oral
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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M de Barrio et al.
Journal of investigational allergology & clinical immunology, 7(3), 193-194 (1997-05-01)
Citiolone (N-acetylhomocysteinethiolactone) is a thiolic-derived medication frequently used in Spain and in other countries as a mucolytic agent for the treatment of certain hepatic disorders. Mucolytic drugs have rarely been implicated in the fixed drug eruption etiology. We report on
U J Eriksson et al.
Diabetologia, 34(5), 325-331 (1991-05-01)
This study addresses the possibility that the teratogenic effects of a diabetic pregnancy are associated with increased embryonic activities of free oxygen radicals. Rat embryos were cultured in 50 mmol/l glucose for 48 h and subsequently showed pronounced growth retardation
Fixed drug eruption due to citiolone.
P G Delgado et al.
Contact dermatitis, 33(5), 352-352 (1995-11-01)
R W Powers et al.
Endocrinology, 137(7), 3101-3110 (1996-07-01)
The activity of nitric oxide (NO) has been implicated as an important mediator in ovarian function, including the regulation of the blood-follicle barrier and ovulation. Both clinical and experimental diabetes have been found to impair endothelial-dependent vascular activity through the
I Flechner et al.
Diabetes research (Edinburgh, Scotland), 13(2), 67-73 (1990-02-01)
The possible value of radical scavengers in the prevention of beta cell destruction was studied in two animal models of type I diabetes. Eight compounds were tested alone or in combinations. In the low-dose streptozotocin model treatment started 24 hr
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