934569

NanoFabTx^™ Photoactivatable Lipid

redAzoPC

• Empirical Formula (Hill Notation): C₄₆H₇₂Cl₄N₃O₈P
• CAS Number: 2839130-47-9
• Molecular Weight: 967.86
• UNSPSC Code: 12161503
• NACRES: NA.21

Properties

• Quality Level: 100
• Assay: ≥90%
• form: solid
• color: orange to dark red
• storage temp.: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@H](OC(CCCC1=CC(Cl)=C(C(Cl)=C1)/N=N/C2=C(C=C(C=C2Cl)CCCC)Cl)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

Description

General description

The NanoFabTx Photoactivatable Lipid, redAzoPC is a red-light photoswitchable lipid for controlled and targeted drug delivery. The tetra-ortho-chloro-azobenzene of redAzoPC can be isomerized from the cis to the trans conformation at 660 nm light. LNPs prepared using the NanoFabTx^™ Photoactivatable Lipid, redAzoPC result in controlled drug release following deep red light irradiation.

Application

Lipid nanoparticle and liposome drug delivery systems

Features and Benefits

• Similar drug loading, encapsulation efficiency, size, and polydispersity to non-photoswitchable lipids
• Light-induced drug delivery
• Targeted and controlled release
• Overcomes limitations associated to UV-switchable lipids

Legal Information

NANOFABTX is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable