Skip to Content
Merck
All Photos(1)

Key Documents

240311

Sigma-Aldrich

Propionic anhydride

≥99%

Synonym(s):

Propanoic anhydride

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
(CH3CH2CO)2O
CAS Number:
Molecular Weight:
130.14
Beilstein:
507066
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

vapor density

4.5 (vs air)

Quality Level

vapor pressure

10 mmHg ( 57.7 °C)

Assay

≥99%

form

liquid

autoignition temp.

545 °F

expl. lim.

11.9 %

refractive index

n20/D 1.404 (lit.)

bp

167 °C (lit.)

mp

−43 °C (lit.)

solubility

chloroform: soluble(lit.)
diethyl ether: soluble(lit.)
ethanol: soluble(lit.)
methanol: soluble(lit.)

density

1.015 g/mL at 25 °C (lit.)

SMILES string

CCC(=O)OC(=O)CC

InChI

1S/C6H10O3/c1-3-5(7)9-6(8)4-2/h3-4H2,1-2H3

InChI key

WYVAMUWZEOHJOQ-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Propionic anhydride (propanoic anhydride) was used in the preparation of α- and β-1-propionyl derivatives of glucopyranose tetra-acetate.

Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

165.2 °F - closed cup

Flash Point(C)

74 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mukundan Ragavan et al.
Metabolites, 11(7) (2021-08-07)
Type II diabetes and pre-diabetes are widely prevalent among adults. Elevated serum glucose levels are commonly treated by targeting hepatic gluconeogenesis for downregulation. However, direct measurement of hepatic gluconeogenic capacity is accomplished only via tracer metabolism approaches that rely on
F Compernolle et al.
The Biochemical journal, 125(3), 811-819 (1971-12-01)
1. The structures of the alpha(2)- and alpha(3)-azopigments, prepared by diazotization of dog bile with ethyl anthranilate, were shown by mass spectrometry and g.l.c. to correspond to azobilirubin beta-d-xylopyranoside and azobilirubin beta-d-glucopyranoside respectively. 2. Both azopigments consist of a mixture
Surendra Nimesh et al.
International journal of pharmaceutics, 337(1-2), 265-274 (2007-01-27)
Polyethylenimine (750 kDa) has been derivatized to influence the proton sponge mechanism and hydrophobic-hydrophilic balance. The polymer was acylated using acid anhydrides of varying carbon chain length, followed by cross-linking with PEG-bis-P to form compact nanoparticles. The chemical linkages in
Haim Tsubery et al.
The Journal of biological chemistry, 279(37), 38118-38124 (2004-06-11)
Polyethylene glycol (PEG)-conjugated therapeutic peptides/proteins have been shown to exhibit clinical properties superior to those of their corresponding unmodified parent molecules. However, the desirable pharmacological features gained by protein PEGylation become irrelevant if conjugates are inactivated or cannot reach their
Mo Xu et al.
Methods in enzymology, 512, 29-55 (2012-08-23)
In eukaryotic cells, posttranslational modifications (PTMs) on histones regulate chromatin structure and thus impact nearly all chromatin-templated events, including replication, transcription, and DNA repair. During S phase, newly synthesized histones are deposited onto DNA, leading to dilution of total chromatin-associated

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service