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USP

Sodium benzoate

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Benzoic acid sodium salt

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About This Item

Linear Formula:
C6H5COONa
CAS Number:
Molecular Weight:
144.10
Beilstein:
3572467
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

sodium benzoate

manufacturer/tradename

USP

mp

>300 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[Na+].[O-]C(=O)c1ccccc1

InChI

1S/C7H6O2.Na/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H,8,9);/q;+1/p-1

InChI key

WXMKPNITSTVMEF-UHFFFAOYSA-M

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Sodium benzoate USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, standard stock, and sensitivity solutions for the assay, and impurity analysis by liquid chromatography in conjunction with a UV detector according to the given below monographs of United States Pharmacopeia (USP):
  • Sodium Benzoate Compounded Oral Solution
  • Pseudoephedrine Hydrochloride Oral Solution
  • Promethazine and Phenylephrine Hydrochloride Oral Solution

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J L Poo et al.
Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion, 42 Suppl, 101-105 (1990-07-01)
Sodium benzoate is widely used in the Alimentary Industry at low doses for its antimicrobial action. It has also been used as a liver function test. The principle is to evaluate the liver capacity for conjugation of glycine to benzoic
Bonnie L Beezhold et al.
Journal of attention disorders, 18(3), 236-241 (2012-04-28)
Sodium benzoate, a common additive in popular beverages, has recently been linked to ADHD. This research examined the relationship between sodium benzoate-rich beverage ingestion and symptoms related to ADHD in college students. College students (N = 475) completed an anonymous
Belinda S Lennerz et al.
Molecular genetics and metabolism, 114(1), 73-79 (2014-12-17)
Sodium benzoate is a widely used preservative found in many foods and soft drinks. It is metabolized within mitochondria to produce hippurate, which is then cleared by the kidneys. We previously reported that ingestion of sodium benzoate at the generally
Susanta Mondal et al.
PloS one, 10(1), e0116566-e0116566 (2015-01-09)
Upregulation and/or maintenance of regulatory T cells (Tregs) during an autoimmune insult may have therapeutic efficacy in autoimmune diseases. Although several immunomodulatory drugs and molecules are available, most present significant side effects over long-term use. Cinnamon is a commonly used
B Nair
International journal of toxicology, 20 Suppl 3, 23-50 (2002-01-05)
Benzyl Alcohol is an aromatic alcohol used in a wide variety of cosmetic formulations as a fragrance component, preservative, solvent, and viscosity-decreasing agent. Benzoic Acid is an aromatic acid used in a wide variety of cosmetics as a pH adjuster

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