1522301

Pheniramine maleate

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): Pheniramine maleate salt
• Empirical Formula (Hill Notation): C₁₆H₂₀N₂ · C₄H₄O₄
• CAS Number: 132-20-7
• Molecular Weight: 356.42
• MDL number: MFCD00079250
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750782
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: pheniramine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: OC(=O)\C=C/C(O)=O.CN(C)CCC(c1ccccc1)c2ccccn2
• InChI: 1S/C16H20N2.C4H4O4/c1-18(2)13-11-15(14-8-4-3-5-9-14)16-10-6-7-12-17-16;5-3(6)1-2-4(7)8/h3-10,12,15H,11,13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
• InChI key: SSOXZAQUVINQSA-BTJKTKAUSA-N
• Gene Information: human ... HRH1(3269)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

• Promethazine HCl solution as an antihistamine research chemical: Promethazine hydrochloride is extensively used in biochemical signaling assays to understand its antihistamine properties, particularly its interaction with histamine H1 receptors, which are critical for alleviating symptoms associated with allergies and motion sickness (Shah et al., 2024).


• In vitro histamine receptor studies: Promethazine hydrochloride solution is utilized in in vitro studies to analyze the blocking effects on histamine receptors, offering insights into its mechanism as a sedative and antiemetic agent. This research is crucial for developing more targeted antihistamine therapies (Altamimy et al., 2024).


• High-purity Promethazine HCl for receptor binding studies: High-purity Promethazine hydrochloride is essential for receptor binding studies to determine its efficacy and potency in binding to receptor sites, which is fundamental for the development of new therapeutic agents that mimic or improve upon its action (Komarov et al., 2023).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable