48586
Aroclor 1254
ampule of 50 mg, analytical standard
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About This Item
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grade
analytical standard
CofA
current certificate can be downloaded
packaging
ampule of 50 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
environmental
format
neat
storage temp.
2-30°C
InChI
1S/C12H5Cl5/c13-8-3-1-2-6(10(8)15)7-4-5-9(14)12(17)11(7)16/h1-5H
InChI key
AUGNBQPSMWGAJE-UHFFFAOYSA-N
General description
Aroclor 1254 is a mixture of several polychlorinated biphenyls, which has been used for chicken embryogenesis and hatching process in order to reduce thyroid hormone levels in blood plasma. It can also work as a powerful inducer of both cytochrome P-448 and P-450 and hence exhibit the catalytic properties of both cytochromes in the liver.
Application
Aroclor 1254 may be used as an analytical standard for the determination of the analyte in pesticide samples and environmental samples by chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Gas chromatograph/mass spectrometer techniques for determination of interferences in pesticide analysis
Analytical Chemistry, 44(3), 603-606 (1972)
Heterogeneity of cytochrome P-450s induced by polychlorinated biphenyls.[Aroclor 1254]
The Journal of Biological Chemistry, 252 (1977)
Effect of in ovo injection of Aroclor 1254 on embryonic development, time of hatching, and blood thyroid hormone levels in one-day-old chicken
Bulletin of the Veterinary Institute in Pulawy, 55, 293-292 (2011)
Journal of toxicology and environmental health. Part B, Critical reviews, 14(5-7), 473-494 (2011-07-28)
Tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin (5-HT) synthesis, performs an essential role in the maintenance of serotonergic functions in the central nervous system (CNS), including regulation of the neuroendocrine system controlling reproduction. The results of recent studies in
Environmental science and pollution research international, 19(3), 628-635 (2011-09-08)
Assessment of environmental impacts from pesticide utilization should include genotoxicity studies, where the possible effects of mutagenic/genotoxic substances on individuals are assessed. In this study, the genotoxicity profile of the new formicide Macex® was evaluated with two genotoxicity tests, namely
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