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X3627

Sigma-Aldrich

Xanthine sodium salt

suitable for cell culture, ≥99%

Synonym(s):

2,6-Dihydroxypurine

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About This Item

Empirical Formula (Hill Notation):
C5H3N4NaO2
CAS Number:
Molecular Weight:
174.09
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51

biological source

synthetic (organic)

Assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤4% methanol

solubility

1 M NaOH: 50 mg/mL, clear to slightly hazy, colorless to light yellow

SMILES string

[Na].O=C1NC(=O)c2[nH]cnc2N1

InChI

1S/C5H4N4O2.Na.H/c10-4-2-3(7-1-6-2)8-5(11)9-4;;/h1H,(H3,6,7,8,9,10,11);;

InChI key

JAZQMXVZANZJSO-UHFFFAOYSA-N

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General description

Xanthine is commonly present in tea, coffee and cocoa. Xanthine is a nitrogenous compound present in blood and urine.

Application

Xanthine sodium salt has been used:
  • as a component in superoxide dismutase (SOD)-inhibitable ferricytochrome c reduction assay
  • as a component in selection of chimeric Modified Vaccinia virus Ankara (MVA)
  • as a substrate in the reaction mixture for xanthine oxidase assay

Biochem/physiol Actions

Xanthine possesses therapeutic properties. It acts as a mild stimulant of the central nervous system.

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Hazard Classifications

STOT SE 2

Target Organs

Eyes

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Modern Pharmacology with Clinical Applications, 351-351 (2004)
Uric acid-lowering effect and intestinal permeability of Kampo medicine, Hachimijiogan, Yokuininto and Goshakusan
Lee SH, et al.
European journal of integrative medicine, 20(1), 193-199 (2018)
Construction of FWPV Chimaeric MVA
Buttigieg KR and Skinner MA
Bio-protocol, 5(1), 65-80 (2015)
Rau's Respiratory Care Pharmacology - E-Book (2013)
Assays for detecting biological superoxide
Zhu H
Reactive Oxygen Species, 1(1), 65-80 (2016)

Articles

Uric acid is not a direct additive to any of the classical cell culture media. However, it is present in animal sera. Consequently, uric acid is typically present in complete serum-supplemented classical cell culture systems.

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