SML1508

C-DIM12

≥98% (HPLC)

• Synonym(s): 3,3′-[(4-Chlorophenyl)methylene]bis-1H-indole, 4-Chlorophenyl-3,3′-diindolylmethane, 4-Chlorophenyldi-3-indolylmethane
• Empirical Formula (Hill Notation): C₂₃H₁₇N₂Cl
• CAS Number: 178946-89-9
• Molecular Weight: 356.85
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825927
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• storage condition: protect from light
• color: , light orange to dark red
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: ClC(C=C1)=CC=C1C(C2=CNC3=C2C=CC=C3)C4=CNC5=C4C=CC=C5
• InChI: 1S/C23H17ClN2/c24-16-11-9-15(10-12-16)23(19-13-25-21-7-3-1-5-17(19)21)20-14-26-22-8-4-2-6-18(20)22/h1-14,23,25-26H
• InChI key: LTLRXTDMXOFBDW-UHFFFAOYSA-N

Description

Biochem/physiol Actions

C-DIM12 is a potent and selective nuclear receptor Nurr1 (NR4A2) activator that activates Nurr1 in urothelial carcinoma cells and in pancreatic cells. C-DIM12 suppresses inflammatory signaling in microglia.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable