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SML0302

Sigma-Aldrich

4-CMTB

≥98% (HPLC)

Synonym(s):

4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide

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About This Item

Empirical Formula (Hill Notation):
C14H15ClN2OS
CAS Number:
300851-67-6
Molecular Weight:
294.80
MDL number:
MFCD02666163
UNSPSC Code:
12352200
PubChem Substance ID:
329825307
NACRES:
NA.77

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to beige

solubility

DMSO: ≥10 mg/mL

storage temp.

2-8°C

SMILES string

CC(C)C(C(=O)Nc1nccs1)c2ccc(Cl)cc2

InChI

1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)

InChI key

AZYDQCGCBQYFSE-UHFFFAOYSA-N

Application

4-CMTB has been used as an allosteric agonist for the free fatty acid receptor 2 (FFAR2) in human lung carcinoma (A549) cells for cell viability assay and Influenza A virus (IAV) internalization studies.

Biochem/physiol Actions

4-CMTB is a phenylacetamide compound that acts as an allosteric modulator for the activity of short-chain fatty acid ligand in the FFA2 receptor.
4-CMTB is a potent allosteric agonist of free fatty acid receptor 2 (FFA2).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302,H319

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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