M3633

4-Methylumbelliferyl β-D-glucopyranoside

β-glucosidase substrate, fluorogenic, ≥99% (HPLC), powder

• Synonym(s): MUD
• Empirical Formula (Hill Notation): C₁₆H₁₈O₈
• CAS Number: 18997-57-4
• Molecular Weight: 338.31
• Beilstein: 94672
• EC Number: 242-736-7
• MDL number: MFCD00063694
• UNSPSC Code: 12352204
• PubChem Substance ID: 24896859
• NACRES: NA.32

Properties

• product name: 4-Methylumbelliferyl β-D-glucopyranoside, β-glucosidase substrate
• Assay: ≥99% (HPLC)
• form: powder
• solubility: DMF: 50 mg/mL, clear, colorless to faintly yellow
• fluorescence: λ_ex 316 nm; λ_em 372 nm (pH 9.1); λ_ex 360 nm; λ_em 449 nm (Reaction product)
• storage temp.: −20°C
• SMILES string: CC1=CC(=O)Oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc12
• InChI: 1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13-,14+,15-,16-/m1/s1
• InChI key: YUDPTGPSBJVHCN-YMILTQATSA-N

Description

Application

4-Methylumbelliferyl β-D-glucopyranoside has been used as substrate:

• in glucosylceramidase β enzyme activity assay in lysosome-enriched fractions from primary hippocampal neurons
• in β-glucosidase assay during yeast fermentation
• to assay glucocerebrosidase 1 (GBA1)-related glucosidase activity in macrophage cell line (RAW)

Biochem/physiol Actions

4-Methylumbelliferyl β-D-glucopyranoside is a synthetic enzymatic substrate for glycosidase. It has been used as substrate for the β- glucosidase from enterococci.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves