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Key Documents

L1567

Sigma-Aldrich

Lipoprotein, high density from human plasma

lyophilized powder

Synonym(s):

α-Lipoprotein, HDL, High density lipoprotein

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About This Item

CAS Number:
308068-14-6
MDL number:
MFCD00164407
UNSPSC Code:
12352202
NACRES:
NA.61

biological source

human plasma

Quality Level

200

Assay

≥95% (agarose gel electrophoresis)

form

lyophilized powder

packaging

vial of ~10 mg protein (modified Lowry)

solubility

0.85% sodium chloride: soluble 10 mg/mL

UniProt accession no.

P02647
P02649
P02654
P02656
P04114
P06727
Q6Q788

storage temp.

2-8°C

Gene Information

human ... APOA1(335) , APOA4(337) , APOA5(116519) , APOB(338) , APOC1(341) , APOC3(345) , APOE(348)

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Biochem/physiol Actions

Lipids are transported in blood plasma among the various tissues by water-soluble complexes called lipoproteins, which differ in size as well as in their composition of lipids and proteins. Each lipoprotein complex contains a distinct number of apolipoproteins and lipid.

Physical form

Lyophilized from a solution of 0.15 M NaCl and 0.01% EDTA, pH 7.4

Other Notes

View more information on lipoprotein function and lipid transport at www.sigma-aldrich.com/enzymeexplorer.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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[Personal requirements of nursing personnel].
B Sturm
Krankenpflege Journal, 26(12), 580-584 (1988-12-01)
Elizebeth C Turner et al.
Molecular biology of the cell, 22(15), 2664-2679 (2011-06-10)
Prostacyclin is increasingly implicated in re-endothelialization and angiogenesis but through largely unknown mechanisms. Herein the high-density lipoprotein (HDL) scavenger receptor class B, type 1 (SR-B1) adapter protein PDZ domain-containing protein 1 (PDZK1) was identified as an interactant of the human
Tao Tan et al.
Nature communications, 10(1), 3322-3322 (2019-07-28)
The tumor stromal microenvironments (TSM) including stromal cells and extracellular matrix (ECM) form an abominable barrier hampering nanoparticles accessibility to cancer cells, significantly compromising their antitumor effects. Herein, we report a bioinspired lipoprotein (bLP) that can induce efficient photothermia to

Articles

Cholesterol Transport

Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are called lipoproteins.

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