G1513
Glycerol formal
47-67% 5-hydroxy-1,3-dioxane basis (GC), 33-53% 4-hydroxymethyl-1,3-dioxolane basis (GC)
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Quality Level
contains
~0.02% 2,6-di-tert-butyl-4-methylphenol as stabilizer
composition
5-hydroxy-1,3-dioxane, 47-67% GC
4-hydroxymethyl-1,3-dioxolane, 33-53% GC
refractive index
n20/D 1.451 (lit.)
bp
192-193 °C (lit.)
density
1.203 g/mL at 25 °C (lit.)
SMILES string
OCC1COCO1.OC2COCOC2
InChI
1S/2C4H8O3/c5-4-1-6-3-7-2-4;5-1-4-2-6-3-7-4/h2*4-5H,1-3H2
InChI key
JIUMSISXCKWZTA-UHFFFAOYSA-N
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General description
Glycerol formal (GlyF) includes isomers, namely, 4-hydroxymethyl-1,3-dioxolane and 5-hydroxy-1,3-dioxane. It is a glycerol synthon with a combination of two 5- and 6-membered ring isomers.
Application
Glycerol formal is used to to solubilize water-insoluble compounds for subsequent aqueous dilution. It has been used as a chemical and dye emulsifier and as a cosolvent for drug delivery. Glycerol formal was used as a vehicle for antibiotic delivery in rats.
WGK
WGK 3
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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