F5135

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala

collagenase substrate, chromogenic

• Synonym(s): FALGPA, N-[3-(2-Furyl)acryloyl]-L-leucyl-glycyl-L-prolyl-L-alanine
• Empirical Formula (Hill Notation): C₂₃H₃₂N₄O₇
• CAS Number: 78832-65-2
• Molecular Weight: 476.52
• MDL number: MFCD00133552
• UNSPSC Code: 12352202
• PubChem Substance ID: 329799652
• NACRES: NA.32

Properties

• product name: N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala,
• UniProt accession no.: Q02111
• storage temp.: −20°C
• SMILES string: CC(C)C[C@H](NC(=O)\C=C\c1ccco1)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](C)C(O)=O
• InChI: 1S/C23H32N4O7/c1-14(2)12-17(26-19(28)9-8-16-6-5-11-34-16)21(30)24-13-20(29)27-10-4-7-18(27)22(31)25-15(3)23(32)33/h5-6,8-9,11,14-15,17-18H,4,7,10,12-13H2,1-3H3,(H,24,30)(H,25,31)(H,26,28)(H,32,33)/b9-8+/t15-,17-,18-/m0/s1
• InChI key: ZLFQNOJSYZSINX-PVJKAEHXSA-N
• Gene Information: mouse ... Prkcq(18761)

Description

Amino Acid Sequence

FA-Leu-Gly-Pro-Ala

General description

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala or FALGPA is a synthetic substance which resemble the primary structure of collagen, and is hydrolyzed by all known collagenases.

Application

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala has been used for use in FALGPA assay performed using GBS (Group B Streptococci) USF704.

Biochem/physiol Actions

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala or FALGPA is hydrolyzed by collagenases and the optimum pH for hydrolysis is 7.4.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Substrates

Substrate for collagenase.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves