COV434
7071909, human ovary, Polygonal & fusiform
Synonym(s):
COV-434 Cells
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About This Item
UNSPSC Code:
41106514
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product name
COV434, 07071909
biological source
human ovary
growth mode
Adherent
karyotype
Modal chromosome no. 47 (46 - 47)
morphology
Polygonal & fusiform
products
Not specified
receptors
Not specified
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
cancer
shipped in
dry ice
storage temp.
−196°C
Cell Line Origin
Human ovarian granulosa tumour
Cell Line Description
Human ovarian granulosa tumour cell line established from a solid primary tumour.
Application
COV434 has been used to study:
- the effect of 17β-estradiol on granulosa cell tumor growth, migration and invasion
- if mutant p53 (inactivatible R248Q hotspot mutation) works as a cancer-specific drug target
- the expression of TLR (toll-like receptor) and its function in the cell line
Culture Medium
DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)
Subculture Routine
Split confluent cultures 1:2 to 1:5 i.e. seeding at 2-4x10,000 cells/cm2 using trypsin/EDTA; 5% CO2; 37°C.
Other Notes
Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.
Certificates of Analysis (COA)
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