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Key Documents

C1006

Sigma-Aldrich

Cytidine 5′-monophosphate disodium salt

Sigma Grade, ≥99%, crystalline

Synonym(s):

C-5′-P, CMP

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About This Item

Linear Formula:
C9H12N3O8PNa2
CAS Number:
Molecular Weight:
367.16
EC Number:
MDL number:
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51

biological source

synthetic

Quality Level

grade

Sigma Grade

Assay

≥99%

form

crystalline

solubility

water: 100 mg/mL, clear to very slightly hazy, colorless to very faintly yellow

storage temp.

2-8°C

SMILES string

[Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(O)=O)C(O)C2O

InChI

1S/C9H14N3O8P.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(20-8)3-19-21(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H2,10,11,15)(H2,16,17,18);;

InChI key

RCIPNLSOCXMZDD-UHFFFAOYSA-N

Application

Cytidine 5′-monophosphate disodium salt has been used:
  • in nucleotide stock solution
  • as an ectonucleotidase (ENTase) inhibitor to probe 5′-ENTase activity in cortical neurons
  • in in vitro studies to estimate its effect on growth response of selected bacteria strains that dominate the piglets′ small intestine

Biochem/physiol Actions

Cytidine 5′-monophosphate (CMP) is used as a substrate of uridine monophosphate (UMP)/cytidine monophosphate (CMP) kinase (EC 2.7.4.4) to form CDP which upon phosphorylation to CTP supports DNA and RNA biosynthesis.
Cytidine monophosphate (CMP) serve as a nucleotide carrier for sugars.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Carbohydrate Metabolism III: Glycoproteins, Glycolipids, GPI Anchors, Proteoglycans, and Peptidoglycans
Medical Biochemistry, 307-330 (2002)
Nucleotides modify growth of selected intestinal bacteria in vitro
Sauer N, et al.
Livestock Science, 133(1), 161-163 (2010)
Nicotinamide riboside, a form of vitamin B3, protects against excitotoxicity-induced axonal degeneration
Vaur P, et al.
Faseb Journal (2017)
Charuni A Amarasekara et al.
Journal of chromatography. A, 1638, 461892-461892 (2021-01-22)
With advances in the design and fabrication of nanofluidic devices during the last decade, there have been a few reports on nucleic acid analysis using nanoscale electrophoresis. The attractive nature of nanofluidics is the unique phenomena associated with this length
P Briozzo et al.
Structure (London, England : 1993), 6(12), 1517-1527 (1998-12-24)
. Nucleoside monophosphate kinases (NMP kinases) catalyze the reversible transfer of a phosphoryl group from a nucleoside triphosphate to a nucleoside monophosphate. Among them, cytidine monophosphate kinase from Escherichia coli has a striking particularity: it is specific for CMP, whereas

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