Skip to Content
Merck
All Photos(1)

Key Documents

36801

Sigma-Aldrich

7-(Diethylamino)coumarin-3-carboxylic acid N-succinimidyl ester

BioReagent, suitable for fluorescence, ≥96.0% (HPLC)

Synonym(s):

N-Succinimidyl 7-(diethylamino)coumarin-3-carboxylate

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C18H18N2O6
CAS Number:
Molecular Weight:
358.35
Beilstein:
5359433
MDL number:
UNSPSC Code:
12352108
PubChem Substance ID:
NACRES:
NA.32

product line

BioReagent

Quality Level

Assay

≥96.0% (HPLC)

solubility

DMF: soluble
DMSO: soluble
acetonitrile: soluble

fluorescence

λex 445 nm; λem 482 nm in 0.1 M phosphate pH 7.0

suitability

corresponds for coupling to amines
suitable for fluorescence

storage temp.

−20°C

SMILES string

CCN(CC)c1ccc2C=C(C(=O)ON3C(=O)CCC3=O)C(=O)Oc2c1

InChI

1S/C18H18N2O6/c1-3-19(4-2)12-6-5-11-9-13(17(23)25-14(11)10-12)18(24)26-20-15(21)7-8-16(20)22/h5-6,9-10H,3-4,7-8H2,1-2H3

InChI key

NUNPVRICKDZFLK-UHFFFAOYSA-N

Application

7-(Diethylamino)coumarin-3-carboxylic acid N-succinimidyl ester is used as a reagent to conjugate 7-(diethylamino)coumarin-3-carboxylic acid (7-DCCA) to other molecules such as amino acids via amide chemistry. 7-DCCA is used to label amino acids prior to resolution by capillary zone electrophoresis. 7-DCCA is used as a reference in screening of nerve agent degradation products by MALDI-TOFMS.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Labeling of amino acids prior to resolution by capillary zone electrophoresis

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

T. Higashijima et al.
Analytical Chemistry, 64, 711-711 (1992)
You-Ren Shu et al.
Analytical chemistry, 78(13), 4697-4701 (2006-07-01)
A novel method for the rapid screening of degradation products derived from nerve agents by matrix-assisted laser desorption ionization time-of-flight mass spectrometry is described. Five standard products were selected as model compounds, including isopropyl methylphosphonic acid (IMPA), pinacolyl methylphosphonic acid

Articles

Fluorescent Labeling of Peptides

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service