04231

Calcium phosphate dibasic dihydrate

puriss., meets analytical specification of Ph. Eur., BP, USP, 98-102.5%

• Synonym(s): Calcium hydrogen phosphate dihydrate
• Linear Formula: CaHPO₄ · 2H₂O
• CAS Number: 7789-77-7
• Molecular Weight: 172.09
• EC Number: 231-826-1
• MDL number: MFCD00149621
• UNSPSC Code: 12352300
• PubChem Substance ID: 329747896
• NACRES: NA.21

Properties

• grade: puriss.
• Quality Level: 200
• Assay: 98-102.5%
• form: powder
• quality: meets analytical specification of Ph. Eur., BP, USP
• impurities: organic volatile impurities, complies; residual solvents, complies; ≤0.003% heavy metals (as Pb); ≤0.1% insoluble in HCl
• loss: 24.5-26.5% loss on ignition, 800 °C
• anion traces: carbonate (CO₃^2-): in accordance; chloride (Cl^-): ≤200 mg/kg; fluoride (F^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤3000 mg/kg
• cation traces: As: ≤1 mg/kg; Ba:, in accordance (Ph Eur); Ba:, in accordance (USP); Fe: ≤300 mg/kg
• SMILES string: O.O.[Ca++].OP([O-])([O-])=O
• InChI: 1S/Ca.H3O4P.2H2O/c;1-5(2,3)4;;/h;(H3,1,2,3,4);2*1H2/q+2;;;/p-2
• InChI key: XAAHAAMILDNBPS-UHFFFAOYSA-L

Description

Application

• Simultaneous Regulation of the Mechanical/Osteogenic Capacity of Brushite Calcium Phosphate Cement by Incorporating with Poly(ethylene glycol) Dicarboxylic Acid: This research investigates enhancing brushite calcium phosphate cements by adding poly(ethylene glycol) dicarboxylic acid to improve mechanical properties and osteogenic capabilities, applicable in bone regeneration and implant materials. (Gao et al., 2024).


• Biosurfactant-Assisted Cu Doping of Brushite Coatings: Explores the structural and biofunctional enhancements of brushite coatings through copper doping facilitated by biosurfactants, which could revolutionize surface treatments for biocompatible implants and devices. (Siva Prasad et al., 2024).


• Self-Healing Micro Arc Oxidation and Dicalcium Phosphate Dihydrate Double-Passivated Coating on Magnesium Membrane for Enhanced Bone Integration Repair: This study highlights the application of calcium phosphate dibasic dihydrate in developing protective coatings on magnesium-based implants, significantly advancing orthopedic and dental implant technologies. (Wu et al., 2024).


• Physiologically Engineered Porous Titanium/Brushite Scaffolds for Critical-Size Bone Defects: Details the design and fabrication of novel scaffolds for treating large bone defects, utilizing a combination of titanium and brushite, highlighting its potential in reconstructive surgery and regenerative medicine. (Abdulaziz et al., 2023).


• Mechanochemical Synthesis of Cerium Chlorapatite from a Mixture of Cerium Chloride Heptahydrate, Dicalcium Phosphate Dihydrate, and Calcium Hydroxide for Biomedical Application: Focuses on the innovative production of cerium chlorapatite using dicalcium phosphate dihydrate, showcasing its potential in biomedical engineering, especially in drug delivery and tissue engineering. (Otsuka et al., 2024).

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable