P45907

Piperazine

ReagentPlus^®, 99%

• Synonym(s): 1,4-Diazacyclohexane, Diethylenediamine
• Empirical Formula (Hill Notation): C₄H₁₀N₂
• CAS Number: 110-85-0
• Molecular Weight: 86.14
• Beilstein: 102555
• EC Number: 203-808-3
• MDL number: MFCD00005953
• UNSPSC Code: 12352100
• eCl@ss: 39160301
• PubChem Substance ID: 24898556
• NACRES: NA.21

Properties

• vapor pressure: 0.8 mmHg ( 20 °C)
• Quality Level: 200
• product line: ReagentPlus^®
• Assay: 99%
• form: solid
• expl. lim.: 14 %
• impurities: <1% water
• pH: 10.8-11.8 (100 g/L)
• bp: 145-146 °C (lit.)
• mp: 109-112 °C (lit.)
• solubility: H₂O: 0.9 g/L at 20 °C
• SMILES string: C1CNCCN1
• InChI: 1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2
• InChI key: GLUUGHFHXGJENI-UHFFFAOYSA-N

Description

General description

Piperazine (PZ) is an amine solvent. The ability of aqueous PZ to absorb carbon dioxide (CO₂) has been assessed. It is reported to cause paralysis in Ascaris worms. The analysis of the crystal structure of PZ at 150K shows the presence of layered structure with NH...N hydrogen-bonded chains.

Application

Intermediate for a wide range of pharmaceuticals, polymers, dyes, corrosion inhibitors, rubber accelerators and surfactants.

Piperazine may be used in the preparation of N-(hetero)arylpiperazines.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS08,GHS05
• Signal Word: Danger
• Hazard Statements: H228,H314,H317,H334,H361fd
• Precautionary Statements: P210 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Flam. Sol. 1 - Repr. 2 - Resp. Sens. 1B - Skin Corr. 1B - Skin Sens. 1B
• Storage Class Code: 4.1B - Flammable solid hazardous materials
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves