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Tetrahexylammonium bromide

suitable for ion pair chromatography, LiChropur, ≥99.0% (AT)

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About This Item

Linear Formula:
[CH3(CH2)5]4N(Br)
CAS Number:
Molecular Weight:
434.58
Beilstein:
3637302
EC Number:
MDL number:
UNSPSC Code:
12000000
PubChem Substance ID:
NACRES:
NB.21

description

cationic

Quality Level

Assay

≥99.0% (AT)

form

crystals

quality

LiChropur

technique(s)

ion pair chromatography: suitable

mp

99-100 °C (lit.)

λ

10 % in methanol

UV absorption

λ: 240 nm Amax: 0.06
λ: 250 nm Amax: 0.04
λ: 260 nm Amax: 0.03
λ: 500 nm Amax: 0.03

suitability

corresponds to standard for filter test

SMILES string

[Br-].CCCCCC[N+](CCCCCC)(CCCCCC)CCCCCC

InChI

1S/C24H52N.BrH/c1-5-9-13-17-21-25(22-18-14-10-6-2,23-19-15-11-7-3)24-20-16-12-8-4;/h5-24H2,1-4H3;1H/q+1;/p-1

InChI key

SYZCZDCAEVUSPM-UHFFFAOYSA-M

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General description

The utilization of ion-pairing reagents as mobile phase additives allows the elution of ionic and highly polar substances using reversed phase HPLC columns. The purity of mobile phase additives is a prime factor to their successful application. Sigma-Aldrich offers an outstanding collection of tailor-made reagents for anionic (quaternary ammonium and phosphonium salts) and cationic (alkanesulfonates) analyzes. All mobile phase additives are rigorously tested with special emphasis on the requirements of modern reversed phase HPLC:

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Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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The effects of tetrahexylammonium chloride on calcium mobilization from cerebellar microsomes.
L G Sayers et al.
Biochemical Society transactions, 21(2), 105S-105S (1993-05-01)
Masamichi Yamanaka et al.
Journal of the American Chemical Society, 126(9), 2939-2943 (2004-03-05)
Resorcinarene 1b forms a hexameric assembly in water-saturated CDCl(3) that encapsulates one tetraalkylammonium salt (2(+)Br(-)). The remaining space is occupied by coencapsulated solvent molecules. A maximum of three and minimum of one CHCl(3) molecule were found inside of capsules with
Zeynep S Teksin et al.
Journal of controlled release : official journal of the Controlled Release Society, 116(1), 50-57 (2006-10-20)
Parallel Artificial Membrane Permeability Assay (PAMPA) is a method to screen drug candidates for membrane permeability. The objective was to characterize the transport of a model weak base, metoprolol, across a three lipid-component PAMPA system (denoted A-PAMPA, for anionic-PAMPA) and
Huiyu Zhou et al.
Journal of pharmaceutical sciences, 91(6), 1502-1511 (2002-07-13)
Inhalation therapy for infectious lung diseases, such as tuberculosis, is currently being explored, with microspheres being used to target alveolar macrophages. One method of drug encapsulation into polymeric microspheres to form hydrophobic ion-paired (HIP) complexes, and then coprecipitate the complex
L G Sayers et al.
Biochimica et biophysica acta, 1152(1), 177-183 (1993-10-10)
In this study we show that the potassium-channel blocker tetrahexyl ammonium chloride (THA+) is able to inhibit inositol 1,4,5-trisphosphate (InsP3)-induced calcium release in an apparently biphasic fashion with a IC50 of 3 microM. This inhibition was not alleviated by valinomycin

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