49797
4-Butylresorcinol
analytical standard
Synonym(s):
4-Butyl-1,3-benzenediol
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About This Item
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grade
analytical standard
Quality Level
Assay
≥97.0% (GC)
shelf life
limited shelf life, expiry date on the label
application(s)
cleaning products
cosmetics
food and beverages
personal care
format
neat
SMILES string
OC1=C(CCCC)C=CC(O)=C1
InChI
1S/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3
InChI key
CSHZYWUPJWVTMQ-UHFFFAOYSA-N
Related Categories
General description
4-n-butylresorcinol is a derivative of resorcinol and a potent human tyrosinase inhibitor. It may be used to decrease skin irritation and is also known to inhibit melanin production.
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 2
Flash Point(F)
293.0 °F
Flash Point(C)
145 °C
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The efficacy and safety of 4-n-butylresorcinol 0.1% cream for the treatment of melasma: a randomized controlled split-face trial.
Annals of Dermatology, 22(1), 21-25 (2010)
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1060, 416-423 (2017-07-05)
In the present study, three laboratories independently compared percutaneous absorption and distribution of 4-n-butylresorcinol, using human skin from five donors. Each laboratory used the same protocol for percutaneous absorption studies but different LC-MS/MS analytical methods to quantify the test compound.
International journal of cosmetic science, 39(3), 248-255 (2016-10-27)
4-n-butylresorcinol is a competitive inhibitor of tyrosinase and has been used as an antimelanogenic agent. However, its inhibition mechanism in intact cells is not fully understood. To elucidate the cellular mechanism, we compared in vitro and in vivo inhibitory effects
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