567152

β-Sitosterol

Common plant steroid that possesses anticholesteremic properties.

• Synonym(s): β-Sitosterol, α-Dihydrofucosterol, 22,23-Dihydrostigmasterol, α-Phytosterol, SITO
• CAS Number: 83-46-5
• MDL number: MFCD00003631
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• Assay: ≥75% (β-sitosterol, GC); ≥95% sterol basis
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• impurities: ≤2.5% (GC)
• color: white
• solubility: chloroform: 5 mg/mL
• shipped in: ambient
• storage temp.: 10-30°C
• InChI: 1S/C29H50O/c1-7-21(19(2)3)9-8-20(4)25-12-13-26-24-11-10-22-18-23(30)14-16-28(22,5)27(24)15-17-29(25,26)6/h10,19-21,23-27,30H,7-9,11-18H2,1-6H3/t20-,21-,23+,24+,25-,26+,27+,28+,29-/m1/s1
• InChI key: KZJWDPNRJALLNS-VJSFXXLFSA-N

Description

General description

Common plant steroid that possesses anticholesteremic properties. Has recently been shown to induce G₂/M arrest, endoreduplication, and apoptosis through the Bcl-2 and PI3K/Akt signaling pathways.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Anticholesteremic properties

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Other Notes

Moon, D., et al. 2008. Cancer Lett.264, 181.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable