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P-044

Supelco

Promethazine hydrochloride

vial of 25 mg, certified reference material, Cerilliant®

Synonym(s):

10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C17H20N2S · HCl
CAS Number:
Molecular Weight:
320.88
Beilstein:
4166397
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:

grade

certified reference material

form

solid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

vial of 25 mg

manufacturer/tradename

Cerilliant®

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

storage temp.

room temp

SMILES string

Cl[H].CC(CN1c2ccccc2Sc3ccccc13)N(C)C

InChI

1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H

InChI key

XXPDBLUZJRXNNZ-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

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General description

Promethazine is a phenothiazine analog prescribed for treatment of motion sickness, nausea, vomiting and allergies. This Certified Reference Material is suitable for GC/MS or LC/MS methods in promethazine testing for forensic analysis, urine drug testing, or clinical toxicology. Sold under the trade names Phenergan® and Phenadoz®, promethazine has antihistamine, sedative, and mild antipsychotic effects. The compound has also been been found in the recreational drug "Purple Drank."

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Phenadoz is a registered trademark of Watson Laboratories, Inc.
Phenergan is a registered trademark of Delcor Asset Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Gaeul Han et al.
Current issues in molecular biology, 43(3), 1669-1684 (2021-10-27)
Postmenopausal syndrome refers to symptoms caused by the gradual decrease in female hormones after mid-40 years. As a target organ of estrogen, decrease in estrogen causes various changes in brain function such as a decrease in choline acetyltransferase and brain-derived
Mario Schietroma et al.
Journal of the American College of Surgeons, 220(5), 921-933 (2015-04-05)
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editor-in-Chief. An independent statistical analysis based on the summary data tables and statistical results reported in the
Cheryl C Y Loh et al.
PloS one, 9(10), e110800-e110800 (2014-10-25)
Chloroquine was a cheap, extremely effective drug against Plasmodium falciparum until resistance arose. One approach to reversing resistance is the inhibition of chloroquine efflux from its site of action, the parasite digestive vacuole. Chloroquine accumulation studies have traditionally relied on
Shigeru Hishinuma et al.
Biochemical pharmacology, 91(2), 231-241 (2014-07-30)
Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and second-generation antihistamines for human
Ana Beatriz Jeronymo-Ceneviva et al.
Probiotics and antimicrobial proteins, 6(3-4), 141-156 (2014-08-15)
This study evaluated the probiotic properties (stability at different pH values and bile salt concentration, auto-aggregation and co-aggregation, survival in the presence of antibiotics and commercial drugs, study of β-galactosidase production, evaluation of the presence of genes encoding MapA and

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