D-103

Desomorphine-D₃ solution

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₇H₁₈D₃NO₂
• CAS Number: 1354573-64-0
• Molecular Weight: 274.37
• EC Number: 200-835-2
• UNSPSC Code: 41116107
• NACRES: NA.24

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: (Snap-N-Spike^®)
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• concentration: 100 μg/mL in acetonitrile
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): forensics and toxicology
• format: single component solution
• storage temp.: −20°C
• SMILES string: OC1=C(O2)C([C@@]3([C@]2([H])CCC4)[C@]4([H])[C@H](N(C([2H])([2H])[2H])CC3)C5)=C5C=C1
• InChI: 1S/C17H21NO2/c1-18-8-7-17-11-3-2-4-14(17)20-16-13(19)6-5-10(15(16)17)9-12(11)18/h5-6,11-12,14,19H,2-4,7-9H2,1H3/t11-,12+,14-,17+/m0/s1/i1D3
• InChI key: LNNWVNGFPYWNQE-ACBFFUFASA-N

Description

General description

A certified reference solution and internal standard for quantificatio of desomorphine levels in urine or other matrices by LC/MS or GC/MS. This stable-labeled internal standard is suitable for opiate testing applications in clinical toxicology, forensic analysis, prescription monitoring, or urine drug testing. Desomorphine, most commonly referred to by its street name Krokodil, is a designer opiate and morphine derivative originally abused in Russia and other parts of Europe due to its ease of manufacture from codeine. Desomorphine was previously sold under the trade name Permonid as an opiate drug for treatment of pain.

Application

• Quantitative analysis of desomorphine in blood and urine using solid phase extraction and gas chromatography-mass spectrometry: Offers a robust analytical methodology for the detection of desomorphine in biological samples, crucial for forensic and clinical toxicology to monitor drug use and facilitate treatment strategies (Winborn J, Kerrigan S, 2019).


• Analysis of Desomorphine in Urine Using Liquid Chromatography-Tandem Mass Spectrometry: Develops an LC-MS/MS method for the efficient detection of desomorphine in urine, providing a sensitive and reliable tool for clinical diagnostics and legal investigations (Winborn J, Kerrigan S, 2019).


• The use of buccal fat pad in surgical treatment of ′Krokodil′ drug-related osteonecrosis of maxilla: Explores innovative surgical interventions to treat severe maxillofacial damage caused by desomorphine, highlighting the reconstructive challenges and the potential for recovery in affected individuals (Hakobyan K, Poghosyan Y, Kasyan A, 2018).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225 - H302 + H312 + H332 - H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 35.6 °F - closed cup
• Flash Point(C): 2.0 °C - closed cup