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C-142

Supelco

Cannabigerolic acid solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

CBGA solution

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About This Item

Empirical Formula (Hill Notation):
C22H32O4
CAS Number:
25555-57-1
Molecular Weight:
360.49
EC Number:
200-835-2
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

(Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

cannabis testing
cannabis testing

format

single component solution

shipped in

dry ice

storage temp.

−70°C

InChI

1S/C22H32O4/c1-5-6-7-11-17-14-19(23)18(21(24)20(17)22(25)26)13-12-16(4)10-8-9-15(2)3/h9,12,14,23-24H,5-8,10-11,13H2,1-4H3,(H,25,26)/b16-12+

InChI key

SEEZIOZEUUMJME-FOWTUZBSSA-N

General description

This Certified Spiking Solution® is suitable for CBGA testing methods by HPLC, LC/MS, or GC/MS for applications in the testing of Cannabis potency or impurity profiling, pharmaceutical research, and forensic analysis. Cerilliant solution Certified Reference Materials (CRMs) of cannabinoids are supplied in a convenient, quantitative, US DEA-exempt solution format and with TK#s for Canadian customers.
Cannabigerolic acid (CBGA) is one of the main cannabinoids that belongs to the class of C21 terpenophenolic compounds. A non-psychoactive cannabinoid, cannabigerolic acid (CBGA), is the precursor to THCA, CBDA, and CBCA cannabinoids in Cannabis. Cannabigerolic acid reportedly has efficacy in the treatment of cancer and schizophrenia.

Application

The Certified Reference Material (CRM) in solution can also be used as follows:
  • Multi-analysis of 11 cannabinoids in biomass and extracts of different cannabis varieties by an HPLC-UV method, following the International Conference on Harmonization (ICH) Tripartite Guideline for Validation of Analytical Procedures
  • High-pressure liquid chromatography (HPLC)- diode array detector (DAD) based quantification of eight cannabinoids in cannabis plant material
  • Determination of eight cannabinoids in hemp samples using reversed phase-high-pressure liquid chromatography (RP-HPLC) in combination with UV detector
  • Extraction of nine cannabinoids from food and beverage samples having hemp seeds, oil, and flour as ingredients followed by their analysis by liquid chromatography-electrospray ionization-QTrap-tandem mass spectrometry LC/ESI‐QTRAP‐MS/MS
  • Gas chromatography-mass spectrometry (GC-MS) based analysis of ten main cannabinoids from hemp inflorescences following their silylation and esterification for derivatization
  • Combination of UV and tandem mass spectrometric (MS/MS) detection with liquid chromatography (LC) for the analysis of major cannabinoids in 13 different cannabidiol-rich commercial products

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

55.0 °F - closed cup

Flash Point(C)

12.8 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

UHPLC Analysis of Cannabinoids on Ascentis Express C18

As the popularity of cannabis-infused products increases, there is a growing need to characterize the type and content of the cannabinoids found in the product. This application demonstrates the ability of the Ascentis Express C18 column to baseline resolve 14 structurally-similar cannabinoids, in under seven minutes, with excellent peak shape.

UHPLC/MS Analysis of Cannabinoids on Ascentis® Express C18

-THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; Cannabichromene solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material

Cannabis Testing

The cannabinoids found in the Cannabis plant commonly referred to as marijuana, have grown in popularity for treating a variety of ailments from arthritis, glaucoma, and chronic pain to malnutrition, multiple sclerosis, and cancer.

HPLC Analysis of Active Cannabinoid Compounds in Gummy Bear Candy on Ascentis® Express Biphenyl with UV Detection after Extraction

Tetrahydrocannabinolic acid A solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material.

Protocols

Analysis of Active Cannabis Compounds in Edible Food Products: Gummy Bears and Brownies

Potency testing in marijuana-infused edibles is an important problem that analytical labs are facing due to the complexity of the involved matrices. Concentration of active ingredients in these edibles can range from a few parts per million to 3.5 parts per thousand. This application demonstrates the extraction and HPLC-UV analysis of the active compounds.

UHPLC/MS Analysis of Cannabinoids Extracted from Raw Cannabis Sativa (Marijuana) on Ascentis® Express RP-Amide

THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; Cannabidiolic acid solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material; Cannabichromene solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; Cannabigerolic acid solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material; Δ9-Tetrahydrocannabinolic acid A (THCA-A)

UHPLC/MS Analysis of Cannabinoids Extracted from Raw Cannabis Sativa (Marijuana) on Ascentis® Express RP-Amide

THC solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; Cannabidiolic acid solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material; Cannabichromene solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; Cannabigerolic acid solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material; Δ9-Tetrahydrocannabinolic acid A (THCA-A)

UHPLC Analysis Cannabinoids Ascentis Express

As the popularity of cannabis-infused products increases, there is a growing need to characterize the type and content of the cannabinoids found in the product. This application demonstrates the ability of the Ascentis Express C18 column to baseline resolve 14 structurally-similar cannabinoids, in under seven minutes, with excellent peak shape.

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