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C-051

Supelco

Caffeine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

SNAP-N-SPIKE®, SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

SMILES string

CN1C(=O)N(C)c2ncn(C)c2C1=O

InChI

1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3

InChI key

RYYVLZVUVIJVGH-UHFFFAOYSA-N

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General description

This Snap-N-Spike® Reference Solution is suitable for use in LC/MS or GC/MS applications from clinical toxicology to dietary supplement testing.

Caffeine belongs to the class of active alkaloid compounds, mainly found in the leaves, fruits, and seeds of about 63 plant species. Coffee beans are the primary source of caffeine, in addition to tea leaves, chocolates, and energy drinks soft drinks. It is a central nervous system stimulant and acts by increasing alertness and reducing sleep.

Application

The Certified Reference Material (CRM) in solution can also be used as follows:
  • To determine caffeine content in an aqueous solution of green coffee beans by two methods based on Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR) and fluorescence spectrophotometry
  • Extraction of caffeine by automated homogeneous liquid-liquid microextraction (A-HLLME) from five different beverage samples for its quantification by high-performance liquid chromatography combined with UV detection
  • Simultaneous estimation of caffeine and chlorogenic acids in ground green coffee samples by a UV/Vis spectrometric method
  • Multi-residue determination of caffeine and paracetamol by square-wave voltammetry using poly(4-amino-3-hydroxynaphthalene sulfonic acid)-modified glassy carbon electrode (poly(AHNSA)/GCE in coca-cola, pepsi, and tea samples
  • Cyclic voltammetric and differential pulse voltammetric based detection and quantitative analysis of paracetamol, tryptophan, and caffeine, both separately and simultaneously, using an electrochemical sensor founded on tin sulfide (SnS)-titanium dioxide (TiO2)-graphene oxide (GO) composite modified glassy carbon electrode

Features and Benefits

  • Fully characterized under ISO/IEC 17025 and ISO 17034 accreditation
  • Accompanied with a comprehensive Certificate of Analysis (CoA) with data on stability, homogeneity, accuracy of concentration, uncertainty, and traceability
  • Rigorously tested through real-time stability studies to ensure accuracy and shelf life
  • Gravimetrically prepared using qualified precision balances to ensure minimal uncertainty
  • Flame sealed under argon into ampoules for long-term shelf life
  • Offered in a convenient, DEA-exempt format to improve laboratory efficiency

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

49.5 °F - closed cup

Flash Point(C)

9.7 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Measures of blood pressure variation have been associated with cardiovascular disease and related outcomes. The regular consumption of black tea can lower blood pressure, but its effects on blood pressure variation have yet to be investigated. We aimed to assess

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