860693P
Avanti
C24:0 Ceramide (d18:2(4E,8Z)/24:0)
Avanti Polar Lipids 860693P, powder
Synonym(s):
N-lignoceroyl-D-erythro-sphingosine (d18:2(4E,8Z) base)
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About This Item
Empirical Formula (Hill Notation):
C42H81NO3
Molecular Weight:
648.10
UNSPSC Code:
12352211
NACRES:
NA.25
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form
powder
packaging
pkg of 1 × 1 mg (860693P-1mg)
manufacturer/tradename
Avanti Polar Lipids 860693P
lipid type
sphingolipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
OC[C@@](NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)([H])[C@]([H])(O)/C=C/CC/C=C\CCCCCCCCC
General description
C24:0 Ceramide (d18:2(4E,8Z)/24:0), also known as N-lignoceroyl-D-erythro-sphingosine (d18:2(4E,8Z) base), is a very long chain plasma ceramide derived from sphingosine containing two double bonds with lignoceric acid.
Biochem/physiol Actions
Altered levels of C24:0 Ceramide has been observed in mild cognitive impairment (MCI) patients. It acts as a primary biomarker of Alzheimer disease (AD) progression.
Packaging
5 mL Amber Glass Screw Cap Vial (860693P-1mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
also commonly purchased with this product
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
No data available
Flash Point(C)
No data available
Certificates of Analysis (COA)
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Michelle M Mielke et al.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 6(5), 378-385 (2010-09-04)
A blood-based biomarker of Alzheimer's disease (AD) would be superior to cerebrospinal fluid (CSF) and neuroimaging measures in terms of cost, invasiveness, and feasibility for repeated measures. We previously reported that blood ceramides varied in relation to timing of memory
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