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300115S

Avanti

Dox-NP™ (5mL vial)

Avanti Research™ - A Croda Brand

Synonym(s):

Dox-NP™ (5mL vial)

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

description

Dox-NP™ (Liposomal Encapsulated Doxorubicin)
frozen liposomal suspension (buffer - 10% w/w sucrose, 10 mM histidine ~pH 6.5)

Assay

>99% (HPLC/MS)

form

dispersion

packaging

pkg of 1 × 5 mL (300115S-1EA)

manufacturer/tradename

Avanti Research™ - A Croda Brand

application(s)

advanced drug delivery

shipped in

dry ice

storage temp.

−20°C

General description

Formulation: A Pegylated, long-circulating liposomal formulation with doxorubicin entrapped within an ammonium sulfate core via remote-loading. All unencapsulated was removed to yield a completely liposomal doxorubicin product. Liposomes are stored frozen for a longer shelf life.

Application

Dox-NP™(5mL vial) has been used as a sample to study its characteristics by asymmetrical-flow field flow fractionation (MD-AF4). It may also be used as an intravenous (i.v.) injection in flank or orthotopic animal models of cancer.

Packaging

10 mL amber serum vial (300115S-1EA)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC
Dox-NP is a trademark of Avanti Polar Lipids, LLC

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Physical characterization of liposomal drug formulations using multi-detector asymmetrical-flow field flow fractionation
Parot J, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society (2020)

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