M73206
4-Methylpiperidine
96%
Synonym(s):
γ-Pipecoline, 4-Pipecoline
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About This Item
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Quality Level
Assay
96%
form
liquid
refractive index
n20/D 1.446 (lit.)
bp
124 °C (lit.)
density
0.838 g/mL at 25 °C (lit.)
SMILES string
CC1CCNCC1
InChI
1S/C6H13N/c1-6-2-4-7-5-3-6/h6-7H,2-5H2,1H3
InChI key
UZOFELREXGAFOI-UHFFFAOYSA-N
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Application
4-Methylpiperidine can be used to synthesize the following bioactive compounds:
It can also act as a deprotecting reagent for the removal of Fmoc group from amino acids during solid-phase peptide synthesis.
- dimethyl bis(4-methylpiperidine-dithiocarbamato-S,S′)-tin(IV)
- (E)-4-(4′-methylpiperidino-N-alkoxy) stilbenes
- 4-methylpiperidinoalkylthio and 4-methylpiperidinoalkoxy derivatives of (E)-chalcone
It can also act as a deprotecting reagent for the removal of Fmoc group from amino acids during solid-phase peptide synthesis.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B
Storage Class Code
3 - Flammable liquids
WGK
WGK 3
Flash Point(F)
55.4 °F - closed cup
Flash Point(C)
13 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Synthesis and antimicrobial activity of new (E)-4-[piperidino (4'-methylpiperidino-, morpholino-) N-alkoxy] stilbenes.
European Journal of Medicinal Chemistry, 41(4), 519-525 (2006)
Efficient synthesis of peptides with 4-methylpiperidine as Fmoc removal reagent by solid phase synthesis.
Journal of the Mexican Chemical Society, 58(4), 386-392 (2014)
Synthesis, physicochemical properties and antimicrobial evaluation of new (E)-chalcones.
European Journal of Medicinal Chemistry, 43(4), 707-713 (2008)
Preparation, Spectroscopy, Antimicrobial Assay, and X-Ray Structure of Dimethyl bis-(4-methylpiperidine dithiocarbamato-S, S)-tin (IV).
Turkish Journal of Chemistry, 31(4), 435-442 (2007)
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